Application of Monoclonal Antibodies in Functional and Comparative Investigations of Heavy-Chain Immunoglobulins in New World Camelids
نویسندگان
چکیده
منابع مشابه
Application of monoclonal antibodies in functional and comparative investigations of heavy-chain immunoglobulins in new world camelids.
Of the three immunoglobulin G (IgG) isotypes described to occur in camelids, IgG2 and IgG3 are distinct in that they do not incorporate light chains. These heavy-chain antibodies (HCAbs) constitute approximately 50% of the IgG in llama serum and as much as 75% of the IgG in camel serum. We have produced isotype-specific mouse monoclonal antibodies (MAbs) in order to investigate the roles of HCA...
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ژورنال
عنوان ژورنال: Clinical and Vaccine Immunology
سال: 2005
ISSN: 1556-6811,1556-679X
DOI: 10.1128/cdli.12.3.380-386.2005